Ivermectin is an antiparasitic medicine on the WHO Model List of Essential Medicines. Its discovery earned Satoshi Ōmura and William C. Campbell a share of the 2015 Nobel Prize in Physiology or Medicine. These guides set out what it is approved for, how it is dosed, what the clinical trials found, and where the evidence is strong or thin — without overstating either.
The two-dose 200 mcg/kg schedule, cure rates of 85–95%, comparison with permethrin, and crusted scabies protocols.
FDA approvedHow ivermectin clears microfilariae, why dosing repeats for years, and the donation programme that eliminated transmission in four countries.
FDA approvedWhy autoinfection makes eradication essential, dosing, and why ivermectin substantially outperforms albendazole here.
FDA approved (topical)Dual antiparasitic and anti-inflammatory action, and the head-to-head trial against metronidazole.
FDA approved (lotion)A single ten-minute application with no nit combing, and why permethrin resistance made it necessary.
Common transient effects, the Mazzotti reaction, when neurotoxicity actually occurs, interactions and overdose signs.
ImportantConcentration, excipients and manufacturing standards — and why horse paste is behind most reported human poisonings.
GMP-certified human formulations — 12 mg, 20 mg and 40 mg tablets and 1% cream. Never veterinary products. Most USA orders ship within 1–7 business days.
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