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308 articles · Updated daily
💉 Azithromycin

Pertussis Exposure: What Azithromycin Prophylaxis Really Does

A close look at who genuinely benefits from post-exposure azithromycin after a whooping cough exposure, the 21-day window that matters, and what CDC guidance actually says.

prophylaxisrespiratory infectionpublic health
✍️ Dr. James Harmon, Research Correspondent · 2026-09-18 Read →
🔭 Praziquantel

Praziquantel Cure Rates: S. mansoni vs Haematobium vs Japonicum

Praziquantel cures schistosomiasis reliably, but not equally. The parasite species, the worm's age, and even the patient's own immune system all shape the outcome.

schistosomiasismechanismdosing
✍️ Dr. James Harmon, Research Correspondent · 2026-09-18 Read →
🩺 Doxycycline

Doxycycline Prophylaxis for Leptospirosis After Flood Exposure

Flooding raises real leptospirosis risk. Here's what the actual trials show about doxycycline as preventive treatment, and where the evidence runs thin.

prophylaxisconditiondosing
✍️ Dr. James Harmon, Research Correspondent · 2026-09-17 Read →
🧬 Hydroxychloroquine

Hydroxychloroquine: One Drug, Two Mechanisms Explained

Hydroxychloroquine fights malaria and calms lupus through the same basic trick: making acidic cellular compartments less acidic.

mechanismautoimmune disease
✍️ Dr. James Harmon, Research Correspondent · 2026-09-17 Read →
🩺 Doxycycline

Doxycycline for Cat-Scratch Disease and Bartonella Infections

Doxycycline is the preferred antibiotic for serious Bartonella infections, though most cat-scratch disease resolves without any drug at all.

conditionmechanism
✍️ Dr. James Harmon, Research Correspondent · 2026-09-17 Read →
💉 Azithromycin

The Morges Strategy: Azithromycin and the Fight to End Yaws

A single oral dose of azithromycin is replacing painful penicillin shots in the global campaign against yaws. Here is what the evidence actually shows.

drug historypublic healthcondition
✍️ Dr. James Harmon, Research Correspondent · 2026-09-17 Read →
⚗️ Mebendazole

Mebendazole's 2011 Reformulation and Its Effect on Absorption

In 2011 mebendazole moved from chewable to film-coated tablets. Here is what changed pharmacologically, and what the evidence actually shows about treatment failures.

drug historydosingformulation
✍️ Dr. James Harmon, Research Correspondent · 2026-09-17 Read →
📄 GermProof

How Skin pH and the Acid Mantle Guide Topical Product Design

The skin's natural acidity shapes which ingredients belong on it. Here's the real science behind pH, the acid mantle, and materials like silver and chitosan.

skin barrierphformulation science
✍️ Dr. James Harmon, Research Correspondent · 2026-09-16 Read →
🩺 Doxycycline

Subantimicrobial Doxycycline: Anti-Inflammatory, Not Antibiotic

Low-dose doxycycline treats rosacea and gum disease through an anti-inflammatory pathway distinct from its antibiotic action—a genuine pharmacological discovery worth understanding.

rosaceadosingmechanism
✍️ Dr. James Harmon, Research Correspondent · 2026-09-16 Read →