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308 articles · Updated daily
💊 Ivermectin

Why Scabies Needs a Second Ivermectin Dose at Day 14

Ivermectin kills scabies mites but not their eggs, so a second dose at day 14 is timed to catch newly hatched mites before they reproduce.

scabiesdosing scheduleparasite lifecycle
✍️ Dr. James Harmon, Research Correspondent · 2026-09-20 Read →
🔬 Fenbendazole

Fenbendazole's Erratic Absorption vs. Albendazole and Mebendazole

Fenbendazole's absorption varies wildly across animal species, unlike the human-tested benzimidazoles albendazole and mebendazole, which have real human pharmacokinetic data.

fenbendazolebioavailabilitypharmacokinetics
✍️ Dr. James Harmon, Research Correspondent · 2026-09-19 Read →
🔭 Praziquantel

Praziquantel's Bitter Taste Problem and the Fix for Children

Praziquantel cures schistosomiasis but tastes so bitter that young children spit it out or vomit it up—new research aims to finally fix that.

praziquantelformulationpediatric dosing
✍️ Dr. James Harmon, Research Correspondent · 2026-09-19 Read →
🩺 Doxycycline

Doxycycline and Q Fever: One Drug, Two Very Different Courses

Doxycycline treats both acute and chronic Q fever, yet one course lasts two weeks and the other lasts years. The biology behind that gap reveals a lot about how infection and immunity interact.

doxycyclineq fevertreatment duration
✍️ Dr. James Harmon, Research Correspondent · 2026-09-19 Read →
⚗️ Mebendazole

Treating Pinworm: Why Household Timing Rivals the Drug

Mebendazole reliably kills adult pinworms, but the cure often fails without simultaneous family dosing and a two-week retreatment. Here's the biology and evidence behind the full protocol.

mebendazolepinwormhousehold treatment
✍️ Dr. James Harmon, Research Correspondent · 2026-09-19 Read →
💊 Ivermectin

Ivermectin Dosing in Obesity: Why the Math Hits a Ceiling

Standard ivermectin doses scale with body weight, but that formula was built on lean study populations. In obesity, the math breaks down in ways worth understanding.

dosingobesitypharmacokinetics
✍️ Dr. James Harmon, Research Correspondent · 2026-09-19 Read →
🩺 Doxycycline

Doxycycline and Pill Esophagitis: Position and Water Matter

Doxycycline can burn the esophagus if it lodges there. Body position and water volume at dosing time change that risk substantially.

safetyadministration techniquegi side effects
✍️ Dr. James Harmon, Research Correspondent · 2026-09-18 Read →
💊 Ivermectin

Moxidectin vs Ivermectin: What Onchocerciasis Trials Show

A landmark head-to-head trial suggests moxidectin suppresses the parasite behind river blindness longer than ivermectin, though it isn't a wholesale replacement yet.

drug comparisononchocerciasisclinical trials
✍️ Dr. James Harmon, Research Correspondent · 2026-09-18 Read →
🌿 Albendazole

Triple-Drug Therapy for Lymphatic Filariasis Explained

Albendazole paired with ivermectin or DEC forms the backbone of global efforts against lymphatic filariasis, each drug attacking the parasite differently.

combination therapyfilariasispublic health
✍️ Dr. James Harmon, Research Correspondent · 2026-09-18 Read →