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308 articles · Updated daily
📄 GermProof

Allergic vs Irritant Contact Dermatitis: What Patch Testing Reveals

Irritant and allergic contact dermatitis look similar but arise differently. Here is how patch testing separates them and what it shows about metals, preservatives, silver and chitosan.

dermatologypatch testingcontact dermatitis
✍️ Dr. James Harmon, Research Correspondent · 2026-10-07 Read →
⚗️ Mebendazole

Mebendazole for Toddlers: Dosing at 12–23 Months and Chewable Tablets

WHO halves the albendazole dose for children aged 12–23 months but keeps mebendazole at 500 mg. Here is why, and how a chewable tablet lowers choking risk for toddlers.

pediatricsdosing principlewho guidance
✍️ Dr. James Harmon, Research Correspondent · 2026-10-05 Read →
💉 Azithromycin

Why Azithromycin Keeps Working After the Last Pill

A short azithromycin course works because the drug builds up inside cells and tissues and leaves slowly. Here is what the research shows, and what it means for patients.

pharmacokineticsdosing principlehalf-life
✍️ Dr. James Harmon, Research Correspondent · 2026-10-05 Read →
🔬 Fenbendazole

How Fenbendazole Kills Parasites: Beta-Tubulin and Oxfendazole

Fenbendazole and its relatives starve parasites by disabling a single protein, beta-tubulin. Here is how that binding works, why it largely spares the host, and what the body turns fenbendazole into.

mechanismpharmacologyveterinary medicine
✍️ Dr. James Harmon, Research Correspondent · 2026-10-05 Read →
🧬 Hydroxychloroquine

Hydroxychloroquine in Lupus Pregnancy: Flares, Safety and Heart Block

For pregnant women with lupus, continuing hydroxychloroquine lowers flare risk and appears safe for the baby. It may also reduce the risk of congenital heart block in anti-Ro-positive mothers.

pregnancylupussafety
✍️ Dr. James Harmon, Research Correspondent · 2026-10-05 Read →
💊 Ivermectin

Loa Loa, Ivermectin and Encephalopathy: Why Test-and-Not-Treat Works

People heavily infected with Loa loa can suffer brain injury after ivermectin. Measuring microfilarial density first, and deferring the few at risk, has made river blindness treatment safer.

safetyloiasisonchocerciasis
✍️ Dr. James Harmon, Research Correspondent · 2026-10-05 Read →
📄 GermProof

Transepidermal Water Loss: How Skin Barrier Function Is Measured

Transepidermal water loss is the laboratory's main measure of skin barrier function. Here is how it is measured, why test conditions matter, and what the readings can and cannot tell you.

skin-barriertewldermatology-research
✍️ Dr. James Harmon, Research Correspondent · 2026-09-30 Read →
🌿 Albendazole

Albendazole Plus Praziquantel for Neurocysticercosis: The Trial Evidence

A randomized trial in Peru found that adding praziquantel to albendazole cleared all brain cysts in more patients with multiple viable cysts. Here is what it showed and what it did not.

neurocysticercosiscombination therapyclinical trials
✍️ Dr. James Harmon, Research Correspondent · 2026-09-28 Read →
🔭 Praziquantel

How Praziquantel Paralyzes Schistosomes: The TRPM Channel Explained

For 40 years no one knew exactly how praziquantel kills blood flukes. Research published in 2021 identified a worm calcium channel as its target, explaining paralysis and skin damage.

mechanismschistosomiasispharmacology
✍️ Dr. James Harmon, Research Correspondent · 2026-09-28 Read →