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308 articles · Updated daily
💊 Ivermectin

The Food Effect: How Fat Changes Ivermectin Absorption

A high-fat meal can raise ivermectin blood levels by roughly 2.5-fold compared to taking it fasting—yet the approved label still says empty stomach.

ivermectinpharmacokineticsdosing
✍️ Dr. James Harmon, Research Correspondent · 2026-07-30 Read →
⚗️ Mebendazole

Mebendazole Dosing and Cure Rates: Pinworm, Whipworm, Roundworm

A close look at mebendazole's actual dosing regimens and documented cure rates for pinworm, whipworm and roundworm, drawn from published clinical evidence.

mebendazoleparasitesdosing
✍️ Dr. James Harmon, Research Correspondent · 2026-07-30 Read →
🔭 Praziquantel

Praziquantel for Tapeworm Infections: How It Works and Is Used

A detailed look at how tapeworms spread, how infections are diagnosed, and how praziquantel treats them—including its history, dosing, and limits.

praziquantelparasitestreatment
✍️ Dr. James Harmon, Research Correspondent · 2026-07-30 Read →
📄 Pharmacology

What Bioequivalence Really Means for Generic Drugs

Generic approval doesn't mean identical—it means statistically equivalent within defined limits. Here's what the FDA standard actually measures, and where it has real limits.

pharmacologygenericsregulation
✍️ Dr. James Harmon, Research Correspondent · 2026-07-30 Read →
💊 Ivermectin

Mectizan Donation Programme: What 4 Billion Doses Proved

Since 1987, Merck's Mectizan Donation Programme has supplied ivermectin free to millions, building the largest human safety record of any anti-parasitic drug.

ivermectinpublic healthsafety
✍️ Dr. James Harmon, Research Correspondent · 2026-07-29 Read →
🩺 Doxycycline

Doxycycline: Lyme Disease, Rickettsia, and Malaria Prevention

A clinical look at doxycycline's role in treating tick-borne infections and preventing malaria, grounded in the actual trial evidence behind each use.

doxycyclineantibioticstreatment
✍️ Dr. James Harmon, Research Correspondent · 2026-07-29 Read →
💊 Ivermectin

Ivermectin and Loa loa: Why Screening Matters Before Treatment

In parts of Central Africa, mass ivermectin treatment can trigger severe reactions in people with heavy Loa loa infection—here's the evidence and how screening solved it.

ivermectinsafetyparasites
✍️ Dr. James Harmon, Research Correspondent · 2026-07-29 Read →
📄 Parasitology

How Mass Drug Administration Interrupts Parasite Transmission

Treating entire communities, not just the visibly sick, has eliminated river blindness and filariasis in whole regions—here is the evidence and its limits.

parasitespublic healthMDA
✍️ Dr. James Harmon, Research Correspondent · 2026-07-29 Read →
💉 Azithromycin

Azithromycin and Antibiotic Stewardship: Why the Course Matters

Azithromycin's unusual chemistry allows short courses to work, but that same chemistry raises real questions about resistance and cardiac safety worth understanding.

azithromycinresistanceantibiotics
✍️ Dr. James Harmon, Research Correspondent · 2026-07-29 Read →