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167 articles · Updated daily
🧬 Hydroxychloroquine

Retinal Screening on Long-Term Hydroxychloroquine: The Guidelines

Hydroxychloroquine can slowly damage the retina in long-term users. Here is what the ophthalmology guidelines actually require, and why the schedule matters.

HCQsafetyophthalmology
✍️ Dr. James Harmon, Research Correspondent · 2026-07-31 Read →
💊 Ivermectin

Crusted Scabies: Why Ivermectin Needs Multiple Doses

Crusted scabies harbors millions of mites and resists single-dose treatment. Here's the biology behind multi-dose ivermectin therapy and how outbreaks begin.

ivermectinscabiesdermatology
✍️ Dr. James Harmon, Research Correspondent · 2026-07-31 Read →
📄 Parasitology

Getting a Real Parasite Diagnosis: Tests and Their Limits

Parasite testing is less straightforward than a simple stool sample. Here is what each test can actually detect, and where each one falls short.

parasitesdiagnosiseducation
✍️ Dr. James Harmon, Research Correspondent · 2026-07-30 Read →
💊 Ivermectin

The Food Effect: How Fat Changes Ivermectin Absorption

A high-fat meal can raise ivermectin blood levels by roughly 2.5-fold compared to taking it fasting—yet the approved label still says empty stomach.

ivermectinpharmacokineticsdosing
✍️ Dr. James Harmon, Research Correspondent · 2026-07-30 Read →
⚗️ Mebendazole

Mebendazole Dosing and Cure Rates: Pinworm, Whipworm, Roundworm

A close look at mebendazole's actual dosing regimens and documented cure rates for pinworm, whipworm and roundworm, drawn from published clinical evidence.

mebendazoleparasitesdosing
✍️ Dr. James Harmon, Research Correspondent · 2026-07-30 Read →
🔭 Praziquantel

Praziquantel for Tapeworm Infections: How It Works and Is Used

A detailed look at how tapeworms spread, how infections are diagnosed, and how praziquantel treats them—including its history, dosing, and limits.

praziquantelparasitestreatment
✍️ Dr. James Harmon, Research Correspondent · 2026-07-30 Read →
📄 Pharmacology

What Bioequivalence Really Means for Generic Drugs

Generic approval doesn't mean identical—it means statistically equivalent within defined limits. Here's what the FDA standard actually measures, and where it has real limits.

pharmacologygenericsregulation
✍️ Dr. James Harmon, Research Correspondent · 2026-07-30 Read →
💊 Ivermectin

Mectizan Donation Programme: What 4 Billion Doses Proved

Since 1987, Merck's Mectizan Donation Programme has supplied ivermectin free to millions, building the largest human safety record of any anti-parasitic drug.

ivermectinpublic healthsafety
✍️ Dr. James Harmon, Research Correspondent · 2026-07-29 Read →
🩺 Doxycycline

Doxycycline: Lyme Disease, Rickettsia, and Malaria Prevention

A clinical look at doxycycline's role in treating tick-borne infections and preventing malaria, grounded in the actual trial evidence behind each use.

doxycyclineantibioticstreatment
✍️ Dr. James Harmon, Research Correspondent · 2026-07-29 Read →